Antenatal mitochondrial disease caused by mitochondrial ribosomal protein (MRPS22) mutation
نویسندگان
چکیده
منابع مشابه
Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming.
Mitochondrial dysfunction caused by pathogenic mutations in mitochondrial tRNA genes emerges only when mutant mitochondrial DNA (mtDNA) proportions exceed intrinsic pathogenic thresholds; however, little is known about the actual proportions of mutant mtDNA that can affect particular cellular lineage-determining processes. Here, we mainly focused on the effects of mitochondrial respiratory dysf...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 2007
ISSN: 1468-6244
DOI: 10.1136/jmg.2007.053116